i ( 6 ) ( p 10 ) Marta Susana Gallego
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چکیده
Etiology It has been suggested that, although the isochromosomes are rarely the sole abnormality in the majority of cases, they do occur early in the leukemic process. Martineau et al. proposed that isochromosomes are mechanical indicators of genetic events central to the etiology of the leukemia. Epidemiology Isochromosomes are a nonrandom chromosomal anomaly in ALL. The incidence of i(6)(p10) in ALL is 0.07%. Only sixteen cases have been reported in ALL and only one in immunoblastic lymphoma. All the patients, except for one adult,
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تاریخ انتشار 2011